Previously you read about how nicotine gum can be used to prevent weight gain. A second significant medication proven to delay post smoking weight gain is Zyban (sustained-release bupropion) (Rigotti 1999). The effects of Zyban on weight gain were evident by 2 months, and Zyban treatment showed a sustained and significant effect up to 1 year after stopping it. People receiving sustained-release bupropion gained an average of 3.2 kg less than the placebo group after 1 year in the study. In those people who remain abstinent from smoking, the group receiving Zyban continued to have significantly less weight gain than the placebo group at the 2-years.

Zyban is better than nicotine replacement products like nicotine patches or sprays in delaying weight gain. The time needed for weight reduction while on Zyban seems to vary with one study suggesting a 7-week treatment while another showed an effect during the first month of treatment. Because bupropion use attenuates weight gain after smoking cessation, this treatment may prove particularly useful among patients who are concerned about weight gain and view this effect as a disincentive to quitting smoking (Rigotti 1999).

Conclusions
Zyban is a proven pharmaceutical agent to help prevent weight gain after quitting smoking. It is more expensive than chewing gum, but it is worth it considering it’s benefit in helping with weight reduction. You can read more about zyban here. Before commencing on this medication, please ask a doctor if it is suitable for you.

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